In Vitro Fertilization and Infertility Center

General Info: 

Our IVF center is staffed with world-class scientists, and uses cutting-edge technology to offer tailor made services that meet the needs and peculiarities of each couple.

In our very hospitable and friendly environment, people reaching out to us feel that their problem will be solved.

Our centers offer top quality service combined with discretion, respect, and understanding, helping you feel “at home”.

The greatest reward for us is the happiness we give to couples who say goodbye after reaching their goal: to have a healthy baby in their arms!

Services offered:

  • Investigation of Female Infertility
  • Investigation of Male Infertility – Semen Analysis – Activation of Sperm Apoptosis Test & DNA Fragmentation in Sperm
  • Semen Cryopreservation
  • Testicular Tissue Cryopreservation
  • Ovulation Monitoring
  • Ovulation Induction
  • Homologous Insemination
  • In Vitro Fertilization (IVF)
  • Intracytoplasmic Sperm Injection (ICSI)
  • IVF in Natural Cycle
  • Insemination with Donor Sperm
  • IVF with Egg Donation
  • IVF with Embryo Donation
  • Embryonic Stem Cell Transfer
  • Preimplantation Genetic Screening (PGS)
  • Preimplantation Genetic Diagnosis (PGD)
  • Assisted Embryo Hatching
  • Freezing of Embryos in all stages of development
  • Frozen Embryo Transfer (FET) in all stages of development
  • Egg Cryopreservation using the Vitrification Method​

The IVF and Infertility Center is one of the first In Vitro Fertilization units in Greece and among the first to operate on an international level. It was established in 1985 by a group of physicians with many years of training in leading UK Centers.

During the long course of the Center’s operation, its physicians had the opportunity to observe, from the very beginning, and to take part in all methods applied in assisted reproduction, with special emphasis on IVF treatment.

The Center operated since 2001 as an integrated unit of the Obstetrics & Gynaecology department within the European Interbalkan Medical Center, in purpose-built facilities. The laboratory adheres to international standards and runs state-of-the-are equipment and culture media. It covers all methods applicable in the field of Assisted Reproduction and is staffed by highly specialized and internationally certified embryologists, who are all trained and have acquired significant experience in major UK Centers.

All doctors of the department are certified by world renowned FMF (Fetal Medicine Foundation) and have been trained in London by Professor Nicolaides. Moreover, FMF is supervising every single case ensuring that pregnant women receive only the highest quality of services. Services include scans and invasive procedures.


In this unit routine and specialized prenatal diagnosis is performed.

  • 6-10 weeks scan. Assessment of viability, prediction of preeclampsia/fetal growth restriction. Down syndrome.
  • 11-13 weeks scan. Assessment of the risk for chromosomal abnormalities, assessment of the risk for preterm delivery and preeclampsia/fetal growth restriction.
  • 20-22 weeks scan. Assessment of structural abnormalities, screening for preterm delivery, preeclampsia/fetal growth restriction.
  • Doppler scan (28-40 weeks). Assessment of placental function, timing of delivery.
  • Specialized fetal echocardiography.

Invasive procedures

  • Diagnostic invasive procedures. Chorionic villus sampling, amniocentesis, fetal blood sampling.
  • Therapeutic invasive procedures. Amniotic fluid drainage, shunt placement for drainage of pathological fluid collections in the fetus (ascites, pleural effusions, hydronephrosis), fetal blood transfusion in fetal anemia, laser coagulation of placental vessels in twin to twin transfusion syndrome.

Related Videos

J.Tzafetas - Obstetrician gynaeclogist - HVF

Professor Kypros Nicolaides - Fetal Medicine Foundation

Greek American citizen gives birth through IVF at Gaia Maternity Clinic – Dr. Konstantinos Pantos

Athens Medical Center

European Interbalkan Medical Center

Professor I. Tzafettas, MD, FRCOG

  • Professor of AUTH
  • Awarded by Athens Academy
  • Founder and former President of Hellenic Representative Committee of Royal College οf Obstetricians and Gynaecologists of London

Dr. Fotis V. Goutzioulis MD


  • Dr.(PhD) of AUTH
  • Has been re-trained and worked in the UK and Belgium

News By Page

In vitro fertilization today: Indications, methods, risks, complications

Written by Goutzioulis Fotios MD, DrMeDObstetrician Gynaecologist, ΙVF & Infertility Center, European Interbalkan Medical Center, Athens Medical Group

It is estimated that in Greece over 10.000 attempts - cycles of IVF are realized every year. The call of society for the use of this method is very strong.

The method of in vitro fertilization (IVF), since its establishment, has spread rapidly around the world and today, nearly four decades later, it is a routine method that has entered the everyday life of many couples. Today, in most Western countries, as in Greece, the application of the methods of in vitro fertilization is regulated by a special law - framework that have established benefits from insurance providers for interested couples.

Without doubt this is an effective method. Today, it is estimated that 80% of couples that will resort to IVF will eventually succeed in having a child, after one or more attempts. Research and development in this scientific field is continuous and intense, while there is a significant improvement in the success rate, compared to what it was two or three decades ago. By means of in vitro fertilization today problems that in the past were impossible to overcome can now be confronted.

In vitro fertilization methods are of a high technology. High scientific knowledge on the part of the specialized reproduction physician are required, but together with team work that combines the skills of the physician, specialized embryologists, specialized paramedical staff, geneticists, with the appropriate technical means such as ultrasounds, autoclaves, microscopes, nutrient mediums, cryopreservation methods. At the same time continual and timely integration of the latest technologies, that are constantly emerging from research is necessary.

It is not necessary for all couples to resort to in vitro fertilization. After trying naturally to conceive for a reasonable period of time, possible causes of reduced fertility of the couple should be sought.

by the physician and, where appropriate, put into practise, and initially exhaust, the most simple methods that could help natural conception, for example, treatment of endometriosis or insemination.

Nevertheless, the demand for in vitro fertilization today seems to be rising and a major reason for this is the postponement of having children and the older age of candidate mothers.

The usual indications for IVF today are:

• Blocked fallopian tubes

• Extensive endometriosis

• Anovulation - difficulty in successful ovulation that is not treatable by other methods

• Male causes - significantly reduced number and motility of sperm

• Unexplained Infertility - when all tests appear normal and simpler methods have not succeeded

• Advanced age of the woman, 40 years and above, where, it is recommended to resort to IVF much sooner

Preimplantation Genetic Diagnosis (PGD)

Dr. Konstantinos Pantos Gynecologist, Director of Infertility Dept., GAIA.

IVF with vehicle the preimplantation genetic diagnosis attempts to “open up” to fertile couples. Several candidates are now parents for whose IVF and preimplantation genetic testing is a choice in order to ensure that the baby will be born healthy.

What is PGD?

In couples at risk of having a child with a serious genetic disease, preimplantation genetic diagnosis eliminates the possibility for the woman to gestate an affected fetus and need to terminate her pregnancy.

Preimplantation diagnosis is the set of techniques applied (ie embryo biopsy and molecular analysis) in order to check the embryos for genetic disorders before their transfer to the uterus. After genetic testing is complete, only normal embryos are transferred into the uterus so that pregnancy can begin safely.

Is it necessary to perform IVF in order to apply pre-implantation genetic diagnosis?

To apply the preimplantation genetic diagnosis it is essential to create fertilized eggs in the laboratory, a process that is achieved with IVF.
Thus, during IVF, biopsy of fertilized eggs and through diagnosis are carried out ​​in the time interval between egg collection and embryo transfer. Genetic analysis is performed on cells obtained through biopsy and based on the results, the embryos which are "healthy", regarding the disease we are looking for, or the diseased ones, are separated. Healthy embryos are then selected for transfer to the uterus.

What is embryo biopsy and when done?

For preimplantation testing be carried out, prior sapling of cells (biopsy) from the embryos is necessary. The biopsy may be done at different stages of embryo development in the laboratory.

The first clinical applications in preimplantation genetic diagnosis, made ​​at the Hammersmith hospital in London, about 15 years ago, emerged from biopsy at the groove stage, i.e. removing one or two cells of the embryo, on the third day after fertilization, and since then it is the most popular method in all centers in the world.

At our center, the method of blastocyst biopsy i.e. removing 5-10 cells from the outer shell of the blastocyst on the 5th day of life of the embryo (blastocyst is the embryo at its 5th day of development after fertilization and consists of 100 -150 cells), comprises a pioneer application since 2004.

What are the indications for preimplantation genetic diagnosis, i.e. what diseases is it applied for?

Practically, one can say that preimplantation diagnosis can be carried out for all genetic diseases, since we know the genetic disorder.

Apart from diagnosis of genetic diseases, has it been applied in other cases?

For example, some years ago it was announced by our center that the first child came to life (was born) in Greece in order to save his sister who suffers from thalassemia.

This couple (both carriers of β thalassemia mutations), had a request to primarily acquire a second healthy child to complete their family while helping their first child who is sick. A mild ovarian stimulation protocol was followed for the woman and then the methods of IVF and biopsy of the fertilized ova. In cell sample from each fertilized egg a screening of mutations for thalassemia was performed and concurrently histocompatibility testing with the existing child in the family. Only one single fertilized egg healthy and histocompatible with the sister was found, which was transferred to the uterus of the woman and a healthy child was born. During childbirth blood was collected from the umbilical cord, from which stem cells were isolated and frozen in order to be transplanted in the future for treatment of the first child.

Through the transplantation of stem cells and hematopoietic tissue, the older child was successfully treated from thalassemia. Already, with the analogous process in two families with sick children with chronic granulomatous disease, where the methodology of preimplantation genetic diagnosis and histocompatibility was applied, the children were successfully treated after transplantation of similar sort. Note that these children usually have a life expectancy until puberty and die as a result of common infections as well as virus infections.

Simultaneously, in Britain the first child, who was tested before implanted in the uterus for whether carrying the genes responsible for breast cancer, was born.

What process was used? Is it applied in our country?

Preimplantation genetic diagnosis is widely applied to exclude genes, which are certain to cause a hereditary disease such as thalassemia. In Britain preimplantation diagnosis was applied to exclude genes, which influence the quality of life expectancy or survival. Genes, i.e., related to cancer, in the particular case of breast cancer, or in other cases, of ovarian or colorectal cancer, or combinations of genes associated with other diseases such as diabetes.

World's first and major achievements of Dr. Pantos’ scientific teem

  • The scientific work is included in the global history of IVF (, i.e. the history of IVF
  • In 2007, ATHENS’ GENESIS attracted the attention of the international news network CNN for the delivery of a healthy child from a LEBER syndrome carrier family bodies that until then had delivered two blind children. The news went around the world through the screens for several days

From Dr. Pantos’ scientific team:

  • the first child in the world was born after blastocyst biopsy free of thalassemia in 2004
  • the first child in the world was born, free of chronic granulomatous disease, which saved its little sister, giving stem cells for transplantation in 2005
  • the first births in the world of healthy children were carried out, which according to their genes, and without our intervention it was likely to suffer from rare genetic diseases such as Cadasil’s disease (2006), congenital adrenal hyperplasia (2006), the maxillofacial dysostosis syndrome FSHD (2007)
  • the first pregnancy in Greece was achieved after preimplantation genetic diagnosis of all chromosomes with the Array-CGH method in 2010.